Ressources numériques en sciences humaines et sociales OpenEdition Nos plateformes OpenEdition Books OpenEdition Journals Hypothèses Calenda Bibliothèques OpenEdition Freemium Suivez-nous

Organoids

A literature review was conducted in March 2022, with such expressions as organoid, iblastoid, organ-on-a-chip or body-on-a-chip in English and in French, in the following databases: Dalloz, Lextenso, HeinOnline, Lexis Nexis, Navis, Lexbase, Cairn, Westlaw, Brill, Doctrinal Plus, BNDS, Wiley, Lamyline, Cambridge University Press Revues, JSTOR, De Gruyter. Please find below the most relevant results of this review.

Alhaque, Sharmin, et al. “Three-Dimensional Cell Culture: From Evolution to Revolution.” Philosophical Transactions: Biological Sciences, vol. 373, no. 1750, 2018, pp. 1–10, http://www.jstor.org/stable/26486297.

Ammar, Jamil. “The Medical Mile Gearing toward 3D-Bespoke Healthcare: A Comparison of United States and European Union Patent Regimes.” Gonzaga Law Review, vol. 52, no. 2, 2017 2016, pp. 279–326, https://heinonline.org/HOL/P?h=hein.journals/gonlr52&i=295.

Ankeny, Rachel A., et al. “Developing a Reflexive, Anticipatory, and Deliberative Approach to Unanticipated Discoveries: Ethical Lessons from IBlastoids.” The American Journal of Bioethics, vol. 22, no. 1, Jan. 2022, pp. 36–45, https://doi.org/10.1080/15265161.2021.1974976.

Ankeny, Rachel A., and Ernst Wolvetang. “Testing the Correlates of Consciousness in Brain Organoids: How Do We Know and What Do We Do?” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 51–53, https://doi.org/10.1080/15265161.2020.1845869.

Ansermet, François, and Ariane Giacobino. “Paniques biotechnologiques.” La Cause du Desir, vol. 93, no. 2, 2016, pp. 55–62, http://www.cairn.info/revue-la-cause-du-desir-2016-2-page-55.htm.

Baniahmad, Aria. “Tumor Spheroids and Organoids as Preclinical Model Systems.” Medizinische Genetik, vol. 33, no. 3, Sept. 2021, pp. 229–34, https://doi.org/10.1515/medgen-2021-2093.

Barnhart, Andrew J., and Kris Dierickx. “A RAD Approach to IBlastoids with a Moral Principle of Complexity.” The American Journal of Bioethics, vol. 22, no. 1, Jan. 2022, pp. 54–56, https://doi.org/10.1080/15265161.2021.2001101.

Birch, Jonathan, and Heather Browning. “Neural Organoids and the Precautionary Principle.” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 56–58, https://doi.org/10.1080/15265161.2020.1845858.

Brown, Grace E., and Salman R. Khetani. “Microfabrication of Liver and Heart Tissues for Drug Development.” Philosophical Transactions: Biological Sciences, vol. 373, no. 1750, 2018, pp. 1–11, http://www.jstor.org/stable/26486306.

Chandler, Jennifer A. “Neurolaw and Neuroethics Symposium: Competing Identities of Neuroethics.” Cambridge Quarterly of Healthcare Ethics, vol. 27, no. 4, 2018, pp. 590–98, https://heinonline.org/HOL/P?h=hein.journals/cqhe27&i=629.

Choi, Kyungsuk. “Ethical and Legal Issues on Human Brain Organoid.” Asia Pacific Journal of Health Law & Ethics, vol. 14, no. 2, 2021 2020, pp. 129–54, https://heinonline.org/HOL/P?h=hein.journals/aspjhle14&i=269.

Clevers, Hans. “On Stem Cells, Organoids and Human Disease.” European Review, vol. 28, no. 1, Feb. 2020, pp. 1–5, https://doi.org/10.1017/S1062798719000231.

Feinberg, Adam W., and Jordan S. Miller. “Progress in Three-Dimensional Bioprinting.” MRS Bulletin, vol. 42, no. 8, Aug. 2017, pp. 557–62, https://doi.org/10.1557/mrs.2017.166.

Felsen, Gidon. “Research Ethics in Conscious Subjects: Old Questions, New Contexts.” The Journal of Law, Medicine & Ethics, vol. 47, no. 4, décembre 2019, pp. 768–70, https://doi.org/10.1177/1073110519897790.

Fins, Joseph J. “Brain Organoids and Consciousness: Late Night Musings Inspired by Lewis Thomas.” Cambridge Quarterly of Healthcare Ethics, vol. 30, no. 4, Oct. 2021, pp. 557–60, https://doi.org/10.1017/S0963180121000037.

Greely, Henry T. “Human Brain Surrogates Research: The Onrushing Ethical Dilemma.” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 34–45, https://doi.org/10.1080/15265161.2020.1845853.

Greely, Henry T. “Hank,” and Karola V. Kreitmair. “Should Cerebral Organoids Be Used for Research If They Have the Capacity for Consciousness?” Cambridge Quarterly of Healthcare Ethics, vol. 30, no. 4, Oct. 2021, pp. 575–84, https://doi.org/10.1017/S0963180121000050.

Green, Sara, et al. “Patient-Derived Organoids in Precision Oncology – Towards a Science of and for the Individual?” Personalized Medicine in the Making, edited by Chiara Beneduce and Marta Bertolaso, vol. 3, Springer International Publishing, 2022, pp. 125–46, https://doi.org/10.1007/978-3-030-74804-3_7.

Koplin, Julian J., and Julian Savulescu. “Moral Limits of Brain Organoid Research.” The Journal of Law, Medicine & Ethics, vol. 47, no. 4, décembre 2019, pp. 760–67, https://doi.org/10.1177/1073110519897789.

Kress, Hartmut. “Xenotransplantation Und Uterustransplantation: Neuland in Der Transplantationsmedizin: Ethischer Klarungs- Und Gesetzlicher Regelungsbedarf New Medical and Biological Technologies.” Jahrbuch Fur Recht Und Ethik, vol. 24, 2016, pp. 113–42, https://heinonline.org/HOL/P?h=hein.journals/jaret24&i=122.

Lauffer, Marlen C. “Organ-on-a-Chip Technologies to Study Neuromuscular Disorders: Possibilities, Limitations, and Future Hopes.” Medizinische Genetik, vol. 33, no. 3, Sept. 2021, pp. 261–67, https://doi.org/10.1515/medgen-2021-2085.

Lavazza, Andrea, and Federico Gustavo Pizzetti. “Human Cerebral Organoids as a New Legal and Ethical Challenge†.” Journal of Law and the Biosciences, vol. 7, no. 1, juillet 2020, p. lsaa005, https://doi.org/10.1093/jlb/lsaa005.

Lee, Tara Sander, et al. “Human Fetal Tissue from Elective Abortions in Research and Medicine: Science, Ethics, and the Law.” Issues in Law & Medicine, vol. 35, no. 1–2, 2020, pp. 3–64, https://heinonline.org/HOL/P?h=hein.journals/ilmed35&i=9.

Lensink, Michael A., et al. “Responsible Research with Human Tissues: The Need for Reciprocity Toward Both Collectives and Individuals.” The American Journal of Bioethics, vol. 21, no. 4, avril 2021, pp. 75–78, https://doi.org/10.1080/15265161.2021.1891346.

Leslie, Jeffrey T. “The Internet and Its Discontents: 3-D Printing, the Commerce Clause, and a Possible Solution to an Inevitable Problem Comment.” SMU Science and Technology Law Review, vol. 17, no. 2, 2014, pp. 195–226, https://heinonline.org/HOL/P?h=hein.journals/comlrtj17&i=205.

Lunshof, Jeantine E. “Brain Surrogates—Empty or Full Makes the Difference.” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 46–48, https://doi.org/10.1080/15265161.2020.1845872.

Lysaght, Tamra. “Anticipatory Governance and Foresight in Regulating for Uncertainty.” The American Journal of Bioethics, vol. 22, no. 1, Jan. 2022, pp. 51–53, https://doi.org/10.1080/15265161.2021.2001111.

Metselaar, Suzanne, et al. “Responding to Human Brain Surrogates Research: The Value of Empirical Ethics.” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 64–66, https://doi.org/10.1080/15265161.2020.1845865.

Mireles, Michael S. “Intellectual Property and Medical Technology: From Creation to Commercialization Introduction.” Wake Forest Journal of Business and Intellectual Property Law, vol. 18, no. 4, 2018 2017, pp. 555–59, https://heinonline.org/HOL/P?h=hein.journals/wakfinp18&i=580.

Monasterio Astobiza, Aníbal, and Alberto Molina Pérez. “Why IBlastoids (Embryo-like Structures) Do Not Rise Significant Ethical Issues.” The American Journal of Bioethics, vol. 22, no. 1, Jan. 2022, pp. 59–61, https://doi.org/10.1080/15265161.2021.2001103.

Nelson, John P., et al. “Amplifying the Call for Anticipatory Governance.” The American Journal of Bioethics, vol. 22, no. 1, Jan. 2022, pp. 48–50, https://doi.org/10.1080/15265161.2021.2001109.

Noah, Lars. “Growing Organs in the Lab: Tissue Engineers Confront Institutional Immune Responses.” Jurimetrics, vol. 55, no. 3, 2015 2014, pp. 297–338, https://heinonline.org/HOL/P?h=hein.journals/juraba55&i=327.

Noor, Fozia. “The Changing Paradigm in Preclinical Toxicology: In Vitro and in Silico Methods in Liver Toxicity Evaluations.” Animal Experimentation, edited by Kathrin Herrmann and Kimberley Jayne, vol. 22, Brill, 2019, pp. 610–38, http://www.jstor.org/stable/10.1163/j.ctvjhzq0f.32.

Nouvel, Pascal. “IV. De l’ingénierie génétique à la thérapie génique.” Science, histoire et societe, 2003, pp. 259–360, http://www.cairn.info/le-possible-et-les-biotechnologies–9782130536260-page-259.htm.

Piotrowska, Monika. “Human Brain Surrogates: Models or Distortions?” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 66–68, https://doi.org/10.1080/15265161.2020.1845867.

Rath, Matthias, and Ute Felbor. “Cellular Models of Genetic Diseases.” Medizinische Genetik, vol. 33, no. 3, Sept. 2021, pp. 219–20, https://doi.org/10.1515/medgen-2021-2095.

Sharma, Arun, et al. “Scientific and Ethical Uncertainties in Brain Organoid Research.” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 48–51, https://doi.org/10.1080/15265161.2020.1845866.

Shuler, Michael L., and James J. Hickman. “Toward in Vitro Models of Brain Structure and Function.” Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 38, 2014, pp. 13682–83, http://www.jstor.org/stable/43043178.

Skeldon, Gregor, et al. “Three-Dimensional Bioprinting of Stem-Cell Derived Tissues for Human Regenerative Medicine.” Philosophical Transactions: Biological Sciences, vol. 373, no. 1750, 2018, pp. 1–11, http://www.jstor.org/stable/26486305.

Vermeulen, Niki, et al. “3D Bioprint Me: A Socioethical View of Bioprinting Human Organs and Tissues.” Journal of Medical Ethics, vol. 43, no. 9, 2017, pp. 618–24, http://www.jstor.org/stable/44606641.

Vinardell Martinez-Hidalgo, Maria Pilar. “Are There Alternatives to Animal Experimentation? Monografico Bioetica y Animales No Humanos En Investigacion, Coordinado Por F. Leyton.” Revista de Bioetica y Derecho, vol. 51, 2021, pp. 81–98, https://heinonline.org/HOL/P?h=hein.journals/rebiod51&i=80.

Wang, Beth. “FDA To Evaluate Organs-On-Chips For Cosmetics, Food Testing.” InsideHealthPolicy.Com’s FDA Week, vol. 23, no. 15, 2017, pp. 14–14, http://www.jstor.org/stable/26702088.

Wilkinson, Malcolm. “The Potential of Organ on Chip Technology for Replacing Animal Testing.” Animal Experimentation, edited by Kathrin Herrmann and Kimberley Jayne, vol. 22, Brill, 2019, pp. 639–53, http://www.jstor.org/stable/10.1163/j.ctvjhzq0f.33.

Xin, Xiaoban. “Patent Eligibility of 3D-Printed Organs Student Notes.” AIPLA Quarterly Journal, vol. 44, no. 1, 2016, p. [i]-170, https://heinonline.org/HOL/P?h=hein.journals/aiplaqj44&i=147.

Zhang, Yu Shrike, et al. “Multisensor-Integrated Organs-on-Chips Platform for Automated and Continual in Situ Monitoring of Organoid Behaviors.” Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 12, 2017, pp. E2293–302, http://www.jstor.org/stable/26480199.

Żuradzki, Tomasz. “Against the Precautionary Approach to Moral Status: The Case of Surrogates for Living Human Brains.” The American Journal of Bioethics, vol. 21, no. 1, Jan. 2021, pp. 53–56, https://doi.org/DOI: 10.1080/15265161.2020.1845868.